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For example, the iron transporter transferrin receptor 1, which is primarily responsible for iron uptake in the form of Fe 3+ -bound transferrin by most cells [18] , exhibits increased expression during ferroptosis and has been proposed as a potential biomarker of ferroptosis [19] , although these data require clinical scrutiny

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Patients with bipolar II depression and anxiety disorder exhibit a lower TSH level and less response to thyrotropin-releasing hormone (TRH), while emotion also influences thyroid hormones (37, 38)